{"id":107245,"date":"2024-06-14T08:48:06","date_gmt":"2024-06-14T08:48:06","guid":{"rendered":"https:\/\/mallorcamedicalgroup.com\/?p=107245"},"modified":"2025-11-25T14:31:10","modified_gmt":"2025-11-25T14:31:10","slug":"innovacion-en-rinoplastia","status":"publish","type":"post","link":"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/","title":{"rendered":"Innovation in Rhinoplasty"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 ez-toc-wrap-left counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Tabla de Contenidos<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Innovation_in_Rhinoplasty\" >Innovation in Rhinoplasty:<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Methods\" >Methods:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Results\" >Results:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Innovation_and_Methodology\" >Innovation and Methodology<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Promising_Results\" >Promising Results<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Clinical_and_Future_Implications\" >Clinical and Future Implications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Some_limitations\" >Some limitations<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Procedural_Complexity\" >Procedural Complexity<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#High_Costs\" >High Costs<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Preparation_Time\" >Preparation Time<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Availability_Limitations\" >Availability Limitations<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"#\" data-href=\"https:\/\/mallorcamedicalgroup.com\/en\/blog\/plastic-surgery-en\/innovacion-en-rinoplastia\/#Insufficient_volume\" >Insufficient volume<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h3><span class=\"ez-toc-section\" id=\"Innovation_in_Rhinoplasty\"><\/span><span style=\"font-weight: 400;\">Innovation in Rhinoplasty:<\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Injectable Cartilaginous Microtissue Regenerated by Autologous Chondrocytes<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A recent 5-year study, published in Plastic and Reconstructive Surgery this June, presents a revolutionary new technique in rhinoplasty: injectable cartilaginous microtissue (ICM). Developed by Dr. Dan Li and his team, this approach uses autologous chondrocytes to regenerate cartilage, offering a minimally invasive solution for nasal augmentation.<\/span><\/p>\n<p><iframe title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/puDipytMw6A?si=ATssQ4haUkP5VZEU\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<h4><span class=\"ez-toc-section\" id=\"Methods\"><\/span><span style=\"font-weight: 400;\">Methods:<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p><span style=\"font-weight: 400;\">&#8211; 1.0 cm\u00b2 of atrial cartilage was collected from 28 patients.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; Isolated chondrocytes were expanded and cultured in chondrogenic media with growth factors for 3 weeks.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; The cultured cartilage is granulated and injected subcutaneously for rhinoplasty.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h4><span class=\"ez-toc-section\" id=\"Results\"><\/span><span style=\"font-weight: 400;\">Results:<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p><span style=\"font-weight: 400;\">&#8211; The ICM was successfully prepared in all patients, efficiently elevating the nasal dorsum.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; MRI confirmed the presence of regenerated tissue, and histological examinations showed mature cartilage formation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; 83.3% of patients reported excellent or good satisfaction during the 5-year follow-up.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; Only two patients (8.3%) experienced remarkable graft absorption.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h4><span class=\"ez-toc-section\" id=\"Innovation_and_Methodology\"><\/span> Innovation and Methodology<span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">The ICM approach uses cultured, granulated autologous cartilage, which allows precise injections for nasal augmentation. The methodology of collecting a small sample of auricular cartilage and expanding chondrocytes in chondrogenic media is remarkable for its ability to generate functional and stable cartilage. This process minimizes the risks associated with graft rejection and infectious complications, critical aspects in rhinoplasty procedures.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h4><span class=\"ez-toc-section\" id=\"Promising_Results\"><\/span><span style=\"font-weight: 400;\"> Promising Results<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">The results of the study are impressive. With a satisfaction rate of 83.3% over five years and only 8.3% remarkable graft absorption, the ICM proves to be an effective and durable technique. Confirmation by MRI and histological examinations showing mature cartilage formation underline the feasibility of this approach in the long term. This finding is crucial since one of the most important limitations in traditional rhinoplasty is graft resorption and the need for surgical revisions.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h4><span class=\"ez-toc-section\" id=\"Clinical_and_Future_Implications\"><\/span><span style=\"font-weight: 400;\"> Clinical and Future Implications<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">The ability to perform nasal augmentations with a minimally invasive approach could have a significant impact on clinical practice. This technique not only offers natural aesthetic results but also reduces recovery time and postoperative complications, which is a great benefit for both patients and surgeons.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">However, although the results are promising, further studies with a larger number of patients and longer follow-up are needed to confirm the long-term stability and safety of MCI. In addition, it would be interesting to explore the applicability of this technique in other reconstructive and aesthetic procedures, which could significantly broaden its impact in plastic surgery.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h4><span class=\"ez-toc-section\" id=\"Some_limitations\"><\/span><span style=\"font-weight: 400;\">Some limitations<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Although the study on injectable cartilage microtissue (ICM) for nasal augmentation shows promising results, it is important to also consider the limitations and possible negative aspects of this technique:<\/span><\/p>\n<p>&nbsp;<\/p>\n<ol>\n<li>\n<h4><span class=\"ez-toc-section\" id=\"Procedural_Complexity\"><\/span><span style=\"font-weight: 400;\"> Procedural Complexity<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">The ICM technique requires a complex and specialized process of chondrocyte culture and microtissue formation. This involves:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; Cartilage Harvesting: The need to harvest auricular cartilage can be uncomfortable and present risks of complications at the harvest site.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; Culture and Granulation: Chondrocyte culture and subsequent cartilage granulation require highly specialized facilities and personnel, which may not be available at all clinical centers.<\/span><\/p>\n<p>&nbsp;<\/p>\n<ol start=\"2\">\n<li>\n<h4><span class=\"ez-toc-section\" id=\"High_Costs\"><\/span><span style=\"font-weight: 400;\"> High Costs<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">The cell culture process and preparation of cartilage microtissue are expensive. Associated costs include:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; Specialized Equipment: Requires advanced equipment for cell culture and microtissue creation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8211; Skilled Labor: The need for highly skilled personnel can increase operating costs.<\/span><\/p>\n<p>&nbsp;<\/p>\n<ol start=\"3\">\n<li>\n<h4><span class=\"ez-toc-section\" id=\"Preparation_Time\"><\/span><span style=\"font-weight: 400;\"> Preparation Time<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">The MCI technique does not offer an immediate solution. Cartilage microtissue preparation takes several weeks, which may not be suitable for all patients. This waiting time can be inconvenient for those seeking faster results.<\/span><\/p>\n<p>&nbsp;<\/p>\n<ol start=\"4\">\n<li>\n<h4><span class=\"ez-toc-section\" id=\"Availability_Limitations\"><\/span><span style=\"font-weight: 400;\"> Availability Limitations<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">Currently, the ICM technique may not be available in all medical centers. This limits its accessibility and widespread use in daily clinical practice. Limited availability may delay the wide-scale adoption and benefits of this technology.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h4><span class=\"ez-toc-section\" id=\"Insufficient_volume\"><\/span><span style=\"font-weight: 400;\"> Insufficient volume<\/span><span class=\"ez-toc-section-end\"><\/span><\/h4>\n<p><span style=\"font-weight: 400;\">It is well known that the effectiveness of nasal torso reconstruction for deep defects requires abundant solid volume.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The images presented in the article show patients with moderate volumes and residual results, valid for the correction of small touch-ups but insufficient for the replacement of large volumes.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Ref: <\/span><\/p>\n<p><a href=\"https:\/\/journals.lww.com\/plasreconsurg\/fulltext\/2024\/06000\/injectable_cartilage_microtissue_regenerated_by.12.aspx?WT.mc_id=EMxALLx20100222xxFRIEND\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Plastic and Reconstructive Surgery <\/span><\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Innovation in Rhinoplasty: Injectable Cartilaginous Microtissue Regenerated by Autologous Chondrocytes A recent 5-year study, published in Plastic and Reconstructive Surgery [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":107258,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[115,118,682],"tags":[136,258,259,260,261,262,263,264,265,266],"class_list":["post-107245","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-plastic-surgery-en","category-rhinoplasty-en","category-consejos-cirugia-plastica-en","tag-rhinoplasty","tag-absorcion-del-injerto-en","tag-augmentacion-nasal-en","tag-cirugia-plastica-en","tag-condrocitos-autologos-en","tag-cultivo-celular-en","tag-microtejido-cartilaginoso-en","tag-regeneracion-de-cartilago-en","tag-resultados-a-largo-plazo-en","tag-tecnica-minimamente-invasiva-en"],"_links":{"self":[{"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/posts\/107245","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/comments?post=107245"}],"version-history":[{"count":6,"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/posts\/107245\/revisions"}],"predecessor-version":[{"id":107261,"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/posts\/107245\/revisions\/107261"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/media\/107258"}],"wp:attachment":[{"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/media?parent=107245"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/categories?post=107245"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mallorcamedicalgroup.com\/en\/wp-json\/wp\/v2\/tags?post=107245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}